ZIA CP010180 01130 (ZIA) | |||
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Title | Prostate cancer pilot study in Africa | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Hsing, Ann | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $299,531 | Project Dates | 09/01/2001 - N/A |
Fiscal Year | 2010 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Aging (5.0%) Biochemical Epidemiology (45.0%) Cancer (100.0%) Diabetes (10.0%) |
Prostate (100.0%) | ||
Research Type | |||
Exogenous Factors in the Origin and Cause of Cancer Endogenous Factors in the Origin and Cause of Cancer |
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Abstract | |||
The general goal of this study is to characterize the burden of prostate cancer in Accra, Ghana, for comparison with other population groups. The specific goals of this study are to 1) estimate the incidence of clinical prostate cancer in Accra, Ghana; 2) characterize the clinical and patholgoical characteristics of prostate cancer cases in Accra, Ghana; 3) screen patients presenting at the Korle-Bu Urology Clinic in Accra with symptoms for prostate cancer or benign prostatic hyperplasia (BPH), using PSA tests, DRE, and biopsy as needed; 4) abstract medical charts for at least 200 biopsy-confirmed prostate cancer cases and 200 BPH cases identified at the Urology Clinic; 5) screen over 1,000 randomly selected men (with the goal of getting consent from 1,000 men) aged 50-74 from the Accra population for prostate cancer and BPH using PSA tests, digital rectal exams, and biopsy confiramation as needed; 6) compare prostate cancer risk in Accra to that of African-Americans in SEER, both before and after 1986, when prostate cancer screening entered widespread use in the U.S. |